(Contd) Hyman M.D., Mark (2023-02-15) Young Forever: THE SUNDAY TIMES BESTSELLER . Hodder & Stoughton: Having a way to measure biological age is essential because without valid ways to measure the effects of any lifestyle or pharmaceutical intervention on our true rate of aging, it would be difficult to draw meaningful conclusions about what works or doesn’t to reverse biological aging. Dr Horvath has discovered a way to measure biological age by measuring the epigenetic clock, also known as the Horvath clock, which reflects how your gene expression changes and interacts with your environment throughout your life. Your lifestyle and environment alter your gene expression. By measuring something called DNA methylation, the chemical tags or bookmarks on your genes that determine which genes are read (turned on) or silenced (turned off), you can determine your biological age. Studies have shown that a few simple functional medicine dietary and lifestyle interventions can reverse biological age (measured by DNA methylation) by three years in just two short months.2 Measuring DNA methylation is available to all of us now, and I encourage you to use it to measure the effects of the Young Forever Program over time (see Part III). Epigenetics: The Master Regulator of Health and Longevity The key to understanding our biological age requires a short primer on genetics: DNA, epigenetics, and a very important biochemical process happening billions of times a second in your body called methylation. Take a ride with me into understanding this critical process that determines nearly everything about our health and longevity. Let’s start at the beginning. Your DNA, also known as your genome. Each of us has a unique genetic code inherited from our parents. Think of your DNA as computer hardware that controls your biological functions. A computer uses a binary code of ones and zeros. Whether you’re typing on a laptop word processor or creating a full-blown Matrix-like virtual reality, it all results from a combination of ones and zeros. Your DNA is exponentially more complex and powerful than computer coding. Your book of life is written with four compounds called nucleotides, represented by the letters A (adenine), G (guanine), C (cytosine), and T (thymine). The average human has 6 billion of these nucleotides with combinations of AGCT that are unique to you. Each gene is comprised of three of these nucleotides linked together in a specific order, such as ACT or GTA. You have about 20,000 genes, much the same as an earthworm. What makes you different from an earthworm are slight variations in the code, spelling changes such as swapping a T for a C that change the function of the proteins produced from that gene. Humans have between 2 and 5 million variations in the letters, or nucleotides, of our genes, which makes us more complex than earthworms. All your DNA does is code for proteins. Proteins not only make our cells and tissues and organs but also are the chemical messengers that regulate nearly everything in our bodies. Each gene is made up of a combination of three letters, such as ATC, which then translate into a specific protein by assembling individual amino acids in a specific order and structure. Even more mind-blowing is the fact that contained within each cell is your entire genetic code, the instructions to create every single part of your body and biology. The cells in your eye contain all the information needed to become bone or muscle or liver. How does your eye know to just be an eye?
The epigenome. Your epigenome. This is the key to understanding how to unlock the secrets of healthy aging and longevity. Human DNA is the hardware and can’t be changed (except with gene editing). The software that runs our life program is the epigenome, which provides instructions to the hardware on what to do. What is the epigenome? Think of it as the keys on your computer keyboard or the keys of a piano. Want to type the word “love” on your computer? You need to enter L‑O‑V‑E on your keyboard. Your keyboard can create gibberish or a Nobel Prize–winning novel or the greatest love poem in history. A piano can create millions of different songs and types of music, from Mozart to reggae to rock to jazz to folk. It all depends on the inputs. Same keys, different results. Your DNA is no different. Your eye, for example, turns off all the genes that make every other organ, and just expresses the part of your DNA (or codes for the proteins) needed to become an optimally functioning eye cell. This is great news because it means we can modify our gene expression—which genes get turned on or off, which story we write in our book of life. A story of disability and disease, or a story of vitality, health, and longevity. The Human Genome Project was one of science’s greatest achievements, but everyone expected that it would unlock the secrets of and cures for disease. How did that turn out? Not so well. Yes, we learned a lot, but most chronic diseases, like heart disease, cancer, diabetes, and dementia, are not the result of a single or even a dozen genes. They are the downstream consequences of changes to your epigenome. It turns out that disease and biological aging are coding problems, instances where there is “corrupt” code in our operating systems. Even though we cannot change our genes (except through gene-editing tools like CRISPR), the fantastic news is that we can change our epigenome, or the coding problem. How? DNA methylation—something we have more control over than you would guess. DNA methylation. DNA methylation is the single most important process controlling your epigenome. Chemical compounds called methyl groups, one carbon and three hydrogen molecules (CH3), wrap around your DNA. These tiny little ubiquitous chemical groups literally control the function of your DNA by telling your body to either activate or silence a gene. The process of DNA methylation is highly influenced by your habits and environment, and it changes throughout your life for better or worse depending on the inputs to your body. It is those changes that help determine your biological age. When methyl groups are added to your DNA, the genes are silenced, or turned off. Similarly, when methyl groups are removed, the genes are turned on. Methylation also regulates DNA protein production and repair, expression of genetic variations, hormones, metabolism, neurotransmitters, detoxification, and energy production. Many enzymes regulate methylation, and those vary greatly from person to person. These enzymes depend on helpers, coenzymes known as methylation factors. Thankfully we get most of these from food, including folate, vitamins B6 and B12, choline, trimethyl glycine, and more. But many of us have variations in our genes that require more or special forms of these methylating nutrients.
DNA methylation is highly influenced by your diet, exercise, stress, relationships, thoughts, nutritional status, toxins, sleep, infections, pretty much everything washing over us as we live our lives. Think of the process of DNA methylation (adding or taking away methyl groups, or CH3) as keystrokes on a piano that change the song played—or how the epigenome translates its effects to the DNA. A single meal or a simple run can change your epigenetic marks by affecting the location of the methyl groups on the DNA or which keys of your piano get played. Even cuddling impacts your DNA methylation! Babies who don’t get enough love and affection are known to have developmental delays and lower IQ—all influenced by changes to their epigenome. Your epigenetics can be positively or negatively influenced at every stage of life. The key is learning what optimizes DNA methylation for health and longevity and shuts down disease. For example, you want the genes for inflammation turned off, while genes that suppress tumors are turned on. That is what you will learn—how to live and be in a way that rewrites your book of life, a story that is full of abundant energy, vibrant health, and a long, active, disease-free existence. Imagine if we modified our habits to turn on all the right genes and turn down the expression of the harmful ones. The result: a long health span and life span. The reason I am taking you down this scientific rabbit hole is to help you understand biological aging and how to reverse it. The overarching concept here is simple. Our genes are fixed. But the genes that are expressed in our book of life, which genes are turned on or off, genes of health and vitality or genes of disease and early death, are modifiable. It turns out that more than 90 percent of chronic disease is determined not by our genome but by our “exposome.”7 Conversely, that means that 90 percent of our health and our potential for longevity results not from our inherited genetic code but from the exposures that influence our genes. The Exposome: The Key to Unlocking Health and Longevity: (This test costs R5.40000. in India: Contact: " getittested,co.in" What is the exposome? It is everything that has happened to you over your lifetime and even what has happened to you in utero or to your ancestors that is imprinted in your epigenome. The trauma of your ancestors is imprinted in their epigenome, and it gets passed on to you. Descendants of concentration camp survivors have their parents’ or grandparents’ trauma imprinted on their genes. The result: They can literally inherit PTSD, anxiety, and depression. Data from multiple studies proves this. And not only emotional trauma is inherited. Animal studies show that exposure to glyphosate, a toxic weed killer used on 70 percent of crops, in grandparents can cause disease in their grandchildren who have never been exposed
Every input influences our epigenome—every bite of food, exercise or lack of exercise, stress, loneliness, toxins, allergens, microbes, our microbiome, our thoughts, feelings, and relationships. Every sadness, every joy. Your senses, your metabolism, the trillions of microbes living in your gut, every chemical exposure, every sunset watched or argument had is registered in real time within your biology and regulates all the switches that control your health, your epigenome. The exposome regulates the epigenome. Your state of health or disease and your biological age are the result of life washing over your genes. And the good news is we have an enormous ability to change those inputs. We can eat whole real food, move our bodies, cut our toxic environmental exposures, heal our traumas, change our thinking and mindset, build community and love in our lives. And these are just first-order interventions. The rapidly progressing science of healthy aging gives us many new “hacks” to improve our epigenome, including supplements, medications, and other novel treatments like hormesis (stress that doesn’t kill you but makes you stronger, like fasting or cold plunges). Although we are less than a decade into the era of measuring our epigenetic biological clocks, a few small but important studies have shown that we can literally reverse our biological age through simple interventions. Steve Horvath and his colleagues gave a group of adults three compounds thought to help with longevity: human growth hormone, DHEA (an adrenal hormone that declines with age), and metformin (a diabetes drug that may have longevity benefits). While I prefer that we use nature-made compounds when possible, certain medications may play a role in treating abnormal aging. What they found in this study astounded them. They expected that perhaps they could slow the biological clock slightly, but they found that they had reduced the biological age of participants by about two and a half years, after a year of treatment, a change that persisted even six months after they stopped treatment.Another study in a typically vitamin D–deficient population found that taking 4,000 IU of vitamin D3 could reduce biological age by 1.85 years in just sixteen weeks. Yet one more study on Polish women showed that a Mediterranean diet could lower biological age by 1.47 years over the course of a year. Their chronological age increased by a year while their biological age reversed. Dr Kara Fitzgerald and her colleagues found even more remarkable results in a study of forty-three healthy adult men between fifty and seventy-two using a comprehensive functional medicine lifestyle intervention. They followed an eight-week treatment program that included a whole foods phytochemical-rich, anti-inflammatory, methylation-supporting diet (an upgrade from the Mediterranean diet), exercise, sleep optimization, stress reduction (breathing techniques), probiotics, and a fruit and vegetable phytonutrient powder with phytochemicals known to improve methylation. The treatment group reversed their biological clock (measured by DNA methylation) by an incredible 3.23 years in just eight weeks compared to the control group.13 Though it was a small study, the results were statistically significant and, frankly, very exciting. Imagine if those changes and other known interventions were combined over many years. How much younger would we be able to become? While the research on the use of the DNA methylation biological clock is in its infancy, it opens the door to an accurate tool that can measure the effects of various interventions on longevity and health. The younger our biology, the healthier we are, the more youthful we feel, the longer we live.
https://www.youtube.com/watch?v=_ofjhmZ50RI Changing Trends in Global Order and India's Strategic Posture | SR Niranjan | AI Impact Summit 2026: (Pease copy URL and paste at Google) Transcript: Welcome to my show. Today we are diving into one of the most defining stories of our time. how the world order is rapidly changing from unipolar dominance to a fragmented multipolar reality and where India actually lands in this shifting landscape. Joining us today is our senior defense0:35 analyst Dr. SR Naranjen. Hello sir. Hello sir. Good evening Jen. Okay. Um and to set the stage um sir how would you describe the major shifts in0:48 the global order as we enter 2026? Sir the stage was set not for 2026. It was set almost 18 20 years ago when the uh great depression or rather to say the 2008 economic collapse or economic meltdown happened in USA. That was the starting point of uh or the foundation was laid for what is today what is happening today that is it dates back to Obama era because he had shifted most of the industries from America to that of China. China was a became the uh what to say the major maker uh mover and shaker around the globe when it comes to production based uh uh sector concerned and at the same time the fall of Japan as a major power as a producing power is something that is a worrying trend and America was partially responsible for what has happened to Japan if not directly indirectly it is responsible say from 1987 uh I think why I'm saying 1987 87 is the peak period of Japan's economy. Virtually it was around five five.5 trillion uh dollars economy whereas America was around 7.88 trillion economy. So subsequent to it you you see the Japanese uh there is a virtually Japanese economy stagnating and there are multiple reasons for it. Let me put three simple reasons. One um the population has not grown drastically. the uh replacement ratio of Japan is has fallen drastically. Mhm. Now the replacement ratio is below one.2:28 uh people who are graduates who are unemployable in Japan who are uh earning their living by working from 7 to 11 uh stores rather to say what we call it as grocery stores whatever stores it is 7-11 stores and that of uh uh unmarried Japanese who go back to that of 80s generation or 70s generation that is uh those who are in the age group of 50 and above has drastically increased. So most of them are living with the pensions that comes through their parents and the life expectancy rate of Japan has grown substantially and new population is not getting added. That's one point where Japan has collapsed. Second, Korea is a economy that was pitted to be a counterpart to Japan by America. But is Korea that big an economy or that big a state to challenge the influence of Japan or for that matter even China? I don't think so. I mean Korea means per say South Korea, not North Korea.
Some people get confused with it. Now comes uh the Europe. Europe is also having a rather to say I consider it as a victimhood tendency that they allowed large scale migrations to take place post uh the ISIS crisis starting from 2014. The migration has been one of the major crisis in Europe. Second crisis is the population crisis. What Japan is facing the similar crisis Europe is also facing. So uh Europe started to incentivize this migration. It is typically like uh what we are facing within our country what we call it as internal migration. We are allowing lot of say for example Tamil Nadu we are allowing lot of other state people especially the Bengali and the Biharis to come and work over here in many sectors that is labor intensive sectors. So most of the jobs are taken up by them. So the the the local population is not having jobs. Either they are not having jobs or they are not inclined to do jobs. Mhm. The same thing uh uh Europe is facing due to the bestian population migrating to that of Europe. And now comes to uh the uh isolated landmass called United States or rather to say the entire America as a continent. So where the problem starts for America is that uh Trump in his first term wanted to reorient America as a uh prime mover and shaker around the world with his policies. I think he did some good things by signing the Abrahamic records wanted to bring peace in the Westian region. U but his folly was he started to take sides and is going back on uh the previous regime's uh agreement between Iran and that of us is something that could have been avoided. Mhm. Because Trump abdegated that agreement. So again he started a fresh crisis over there. Now the second time he is I think he's over ambitious. Post coid America has not learned its lessons. America's crisis is two fold crisis as far as I study it. First is the population crisis. here is no enough population in America. And he wants to cail the migration. At the same time, Americans are not reproducing. Even if they are reproducing, there the the uh reproduction ratio of colored people is more than that of the Anglo-Saxon whites. M6:19 and you can see the racial crimes against Indians also growing in America is because of this factor. That's one part. Second part is that because they had outsourced their entire production to that of China. Trump by hook a crook wants to bring back the production sector back to that of United States. But wheels within wheels the other crisis that America is facing is the domination of dollar is getting over. America's rise as a predominant power is directly uh uh related to that of the price of dollar as a global currency. If not for Henry Kissinger and Richard Nixon, people may hate them, people may love them, but we cannot ignore both the two individuals. As a as an individual, I do have my distaste towards how Kissinger or Nixon had treated India during the 1971 war. But for Americans, it was a game changer tenure because he had decoupled the dollar with that of the gold standard. And Kissinger was very much responsible for bringing in relating making the dollar uh as a currency through which petrol can be I mean crude oil can be marketed around the world. But now when Trump took power that a meltdown had started the West Asian powers or West Asian countries the oil producing economies they started to deviate from their normal trend of using dollar as a currency. So they started to deal with their own form of trading between the uh major oil consuming economies. Major oil consuming economies per se is it is nothing. It is not some kind of a what to say uh you need not
6 comments:
(Contd) Hyman M.D., Mark (2023-02-15) Young Forever: THE SUNDAY TIMES BESTSELLER . Hodder & Stoughton: Having a way to measure biological age is essential because without valid ways to measure the effects of any lifestyle or pharmaceutical intervention on our true rate of aging, it would be difficult to draw meaningful conclusions about what works or doesn’t to reverse biological aging. Dr Horvath has discovered a way to measure biological age by measuring the epigenetic clock, also known as the Horvath clock, which reflects how your gene expression changes and interacts with your environment throughout your life. Your lifestyle and environment alter your gene expression. By measuring something called DNA methylation, the chemical tags or bookmarks on your genes that determine which genes are read (turned on) or silenced (turned off), you can determine your biological age. Studies have shown that a few simple functional medicine dietary and lifestyle interventions can reverse biological age (measured by DNA methylation) by three years in just two short months.2 Measuring DNA methylation is available to all of us now, and I encourage you to use it to measure the effects of the Young Forever Program over time (see Part III). Epigenetics: The Master Regulator of Health and Longevity The key to understanding our biological age requires a short primer on genetics: DNA, epigenetics, and a very important biochemical process happening billions of times a second in your body called methylation. Take a ride with me into understanding this critical process that determines nearly everything about our health and longevity. Let’s start at the beginning. Your DNA, also known as your genome. Each of us has a unique genetic code inherited from our parents. Think of your DNA as computer hardware that controls your biological functions. A computer uses a binary code of ones and zeros. Whether you’re typing on a laptop word processor or creating a full-blown Matrix-like virtual reality, it all results from a combination of ones and zeros. Your DNA is exponentially more complex and powerful than computer coding. Your book of life is written with four compounds called nucleotides, represented by the letters A (adenine), G (guanine), C (cytosine), and T (thymine). The average human has 6 billion of these nucleotides with combinations of AGCT that are unique to you. Each gene is comprised of three of these nucleotides linked together in a specific order, such as ACT or GTA. You have about 20,000 genes, much the same as an earthworm. What makes you different from an earthworm are slight variations in the code, spelling changes such as swapping a T for a C that change the function of the proteins produced from that gene. Humans have between 2 and 5 million variations in the letters, or nucleotides, of our genes, which makes us more complex than earthworms. All your DNA does is code for proteins. Proteins not only make our cells and tissues and organs but also are the chemical messengers that regulate nearly everything in our bodies. Each gene is made up of a combination of three letters, such as ATC, which then translate into a specific protein by assembling individual amino acids in a specific order and structure. Even more mind-blowing is the fact that contained within each cell is your entire genetic code, the instructions to create every single part of your body and biology. The cells in your eye contain all the information needed to become bone or muscle or liver. How does your eye know to just be an eye?
The epigenome. Your epigenome. This is the key to understanding how to unlock the secrets of healthy aging and longevity. Human DNA is the hardware and can’t be changed (except with gene editing). The software that runs our life program is the epigenome, which provides instructions to the hardware on what to do. What is the epigenome? Think of it as the keys on your computer keyboard or the keys of a piano. Want to type the word “love” on your computer? You need to enter L‑O‑V‑E on your keyboard. Your keyboard can create gibberish or a Nobel Prize–winning novel or the greatest love poem in history. A piano can create millions of different songs and types of music, from Mozart to reggae to rock to jazz to folk. It all depends on the inputs. Same keys, different results. Your DNA is no different. Your eye, for example, turns off all the genes that make every other organ, and just expresses the part of your DNA (or codes for the proteins) needed to become an optimally functioning eye cell. This is great news because it means we can modify our gene expression—which genes get turned on or off, which story we write in our book of life. A story of disability and disease, or a story of vitality, health, and longevity. The Human Genome Project was one of science’s greatest achievements, but everyone expected that it would unlock the secrets of and cures for disease. How did that turn out? Not so well. Yes, we learned a lot, but most chronic diseases, like heart disease, cancer, diabetes, and dementia, are not the result of a single or even a dozen genes. They are the downstream consequences of changes to your epigenome. It turns out that disease and biological aging are coding problems, instances where there is “corrupt” code in our operating systems. Even though we cannot change our genes (except through gene-editing tools like CRISPR), the fantastic news is that we can change our epigenome, or the coding problem. How? DNA methylation—something we have more control over than you would guess. DNA methylation. DNA methylation is the single most important process controlling your epigenome. Chemical compounds called methyl groups, one carbon and three hydrogen molecules (CH3), wrap around your DNA. These tiny little ubiquitous chemical groups literally control the function of your DNA by telling your body to either activate or silence a gene. The process of DNA methylation is highly influenced by your habits and environment, and it changes throughout your life for better or worse depending on the inputs to your body. It is those changes that help determine your biological age. When methyl groups are added to your DNA, the genes are silenced, or turned off. Similarly, when methyl groups are removed, the genes are turned on. Methylation also regulates DNA protein production and repair, expression of genetic variations, hormones, metabolism, neurotransmitters, detoxification, and energy production. Many enzymes regulate methylation, and those vary greatly from person to person. These enzymes depend on helpers, coenzymes known as methylation factors. Thankfully we get most of these from food, including folate, vitamins B6 and B12, choline, trimethyl glycine, and more. But many of us have variations in our genes that require more or special forms of these methylating nutrients.
DNA methylation is highly influenced by your diet, exercise, stress, relationships, thoughts, nutritional status, toxins, sleep, infections, pretty much everything washing over us as we live our lives. Think of the process of DNA methylation (adding or taking away methyl groups, or CH3) as keystrokes on a piano that change the song played—or how the epigenome translates its effects to the DNA. A single meal or a simple run can change your epigenetic marks by affecting the location of the methyl groups on the DNA or which keys of your piano get played. Even cuddling impacts your DNA methylation! Babies who don’t get enough love and affection are known to have developmental delays and lower IQ—all influenced by changes to their epigenome. Your epigenetics can be positively or negatively influenced at every stage of life. The key is learning what optimizes DNA methylation for health and longevity and shuts down disease. For example, you want the genes for inflammation turned off, while genes that suppress tumors are turned on. That is what you will learn—how to live and be in a way that rewrites your book of life, a story that is full of abundant energy, vibrant health, and a long, active, disease-free existence. Imagine if we modified our habits to turn on all the right genes and turn down the expression of the harmful ones. The result: a long health span and life span. The reason I am taking you down this scientific rabbit hole is to help you understand biological aging and how to reverse it. The overarching concept here is simple. Our genes are fixed. But the genes that are expressed in our book of life, which genes are turned on or off, genes of health and vitality or genes of disease and early death, are modifiable. It turns out that more than 90 percent of chronic disease is determined not by our genome but by our “exposome.”7 Conversely, that means that 90 percent of our health and our potential for longevity results not from our inherited genetic code but from the exposures that influence our genes. The Exposome: The Key to Unlocking Health and Longevity: (This test costs R5.40000. in India: Contact: " getittested,co.in" What is the exposome? It is everything that has happened to you over your lifetime and even what has happened to you in utero or to your ancestors that is imprinted in your epigenome. The trauma of your ancestors is imprinted in their epigenome, and it gets passed on to you. Descendants of concentration camp survivors have their parents’ or grandparents’ trauma imprinted on their genes. The result: They can literally inherit PTSD, anxiety, and depression. Data from multiple studies proves this. And not only emotional trauma is inherited. Animal studies show that exposure to glyphosate, a toxic weed killer used on 70 percent of crops, in grandparents can cause disease in their grandchildren who have never been exposed
Every input influences our epigenome—every bite of food, exercise or lack of exercise, stress, loneliness, toxins, allergens, microbes, our microbiome, our thoughts, feelings, and relationships. Every sadness, every joy. Your senses, your metabolism, the trillions of microbes living in your gut, every chemical exposure, every sunset watched or argument had is registered in real time within your biology and regulates all the switches that control your health, your epigenome. The exposome regulates the epigenome. Your state of health or disease and your biological age are the result of life washing over your genes. And the good news is we have an enormous ability to change those inputs. We can eat whole real food, move our bodies, cut our toxic environmental exposures, heal our traumas, change our thinking and mindset, build community and love in our lives. And these are just first-order interventions. The rapidly progressing science of healthy aging gives us many new “hacks” to improve our epigenome, including supplements, medications, and other novel treatments like hormesis (stress that doesn’t kill you but makes you stronger, like fasting or cold plunges). Although we are less than a decade into the era of measuring our epigenetic biological clocks, a few small but important studies have shown that we can literally reverse our biological age through simple interventions. Steve Horvath and his colleagues gave a group of adults three compounds thought to help with longevity: human growth hormone, DHEA (an adrenal hormone that declines with age), and metformin (a diabetes drug that may have longevity benefits). While I prefer that we use nature-made compounds when possible, certain medications may play a role in treating abnormal aging. What they found in this study astounded them. They expected that perhaps they could slow the biological clock slightly, but they found that they had reduced the biological age of participants by about two and a half years, after a year of treatment, a change that persisted even six months after they stopped treatment.Another study in a typically vitamin D–deficient population found that taking 4,000 IU of vitamin D3 could reduce biological age by 1.85 years in just sixteen weeks. Yet one more study on Polish women showed that a Mediterranean diet could lower biological age by 1.47 years over the course of a year. Their chronological age increased by a year while their biological age reversed. Dr Kara Fitzgerald and her colleagues found even more remarkable results in a study of forty-three healthy adult men between fifty and seventy-two using a comprehensive functional medicine lifestyle intervention. They followed an eight-week treatment program that included a whole foods phytochemical-rich, anti-inflammatory, methylation-supporting diet (an upgrade from the Mediterranean diet), exercise, sleep optimization, stress reduction (breathing techniques), probiotics, and a fruit and vegetable phytonutrient powder with phytochemicals known to improve methylation. The treatment group reversed their biological clock (measured by DNA methylation) by an incredible 3.23 years in just eight weeks compared to the control group.13 Though it was a small study, the results were statistically significant and, frankly, very exciting. Imagine if those changes and other known interventions were combined over many years. How much younger would we be able to become? While the research on the use of the DNA methylation biological clock is in its infancy, it opens the door to an accurate tool that can measure the effects of various interventions on longevity and health. The younger our biology, the healthier we are, the more youthful we feel, the longer we live.
https://www.youtube.com/watch?v=_ofjhmZ50RI Changing Trends in Global Order and India's Strategic Posture | SR Niranjan | AI Impact Summit 2026: (Pease copy URL and paste at Google) Transcript: Welcome to my show. Today we are diving into one of the most defining stories of our time. how the world order is rapidly changing from unipolar dominance to a fragmented multipolar reality and where India actually lands in this shifting landscape. Joining us today is our senior defense0:35
analyst Dr. SR Naranjen. Hello sir. Hello sir. Good evening Jen. Okay. Um and to set the stage um sir how would you describe the major shifts in0:48
the global order as we enter 2026? Sir the stage was set not for 2026. It was set almost 18 20 years ago when the uh great depression or rather to say the
2008 economic collapse or economic meltdown happened in USA. That was the starting point of uh or the foundation was laid for what is today what is happening today that is it dates back to Obama era because he had shifted most of the industries from America to that of China. China was a became the uh what to say the major maker uh mover and shaker around the globe when it comes to production based uh uh sector concerned and at the same time the fall of Japan as a major power as a producing power is something that is a worrying trend and America was partially responsible for what has happened to Japan if not directly indirectly it is responsible say from 1987 uh I think why I'm saying 1987 87 is the peak period of Japan's economy. Virtually it was around five five.5 trillion uh dollars economy whereas America was around 7.88 trillion economy. So subsequent to it you you see
the Japanese uh there is a virtually Japanese economy stagnating and there are multiple reasons for it. Let me put three simple reasons. One um the population has not grown drastically. the uh replacement ratio of Japan is has fallen drastically. Mhm. Now the replacement ratio is below one.2:28
uh people who are graduates who are unemployable in Japan who are uh earning their living by working from 7 to 11 uh stores rather to say what we call it as grocery stores whatever stores it is 7-11 stores and that of uh uh unmarried Japanese who go back to that of 80s generation or 70s generation that is uh those who are in the age group of 50 and above has drastically increased. So most of them are living with the pensions that comes through their parents and the life expectancy rate of Japan has grown substantially and new population is not getting added. That's one point where Japan has collapsed. Second, Korea is a economy that was pitted to be a counterpart to Japan by America. But is Korea that big an economy or that big a state to challenge the influence of Japan or for that matter even China? I don't think so. I mean Korea means per say South Korea, not North Korea.
Some people get confused with it. Now comes uh the Europe. Europe is also
having a rather to say I consider it as a victimhood tendency that they allowed large scale migrations to take place post uh the ISIS crisis starting from 2014. The migration has been one of the major crisis in Europe. Second crisis is the population crisis. What Japan is facing the similar crisis Europe is also facing. So uh Europe started to incentivize this migration. It is typically like uh what we are facing within our country what we call it as internal migration. We are allowing lot of say for example Tamil Nadu we are allowing lot of other state people especially the Bengali and the Biharis to come and work over here in many sectors that is labor intensive sectors. So most of the jobs are taken up by them. So the the the local population is not having jobs. Either they are not having jobs or they are not inclined to do jobs. Mhm. The same thing uh uh Europe is facing due to the bestian population migrating to that of Europe. And now comes to uh the uh isolated landmass called United States or rather to say the entire America as a continent. So where the problem starts for America is that uh Trump in his first term wanted to reorient America as a uh prime mover and shaker around the world with his policies. I think he did some good things by signing the Abrahamic records wanted to bring peace in the Westian region. U but his folly was he started to take sides and is going back on uh the previous regime's uh agreement between Iran and that of us is something that could have been avoided. Mhm. Because Trump abdegated that agreement.
So again he started a fresh crisis over there. Now the second time he is I think he's over ambitious. Post coid America has not learned its lessons. America's crisis is two fold crisis as far as I study it. First is the population crisis. here is no enough population in America. And he wants to cail the migration. At the same time, Americans are not reproducing. Even if they are reproducing, there the the uh reproduction ratio of colored people is more than that of the Anglo-Saxon whites. M6:19
and you can see the racial crimes against Indians also growing in America is because of this factor. That's one part. Second part is that because they had outsourced their entire production to that of China. Trump by hook a crook wants to bring back the production sector back to that of United States. But wheels within wheels the other crisis that America is facing is the domination of dollar is getting over. America's rise as a predominant power is directly uh uh related to that of the price of dollar as a global currency. If not for Henry Kissinger and Richard Nixon, people may hate them, people may love them, but we cannot ignore both the two individuals. As a as an individual, I do have my distaste towards how Kissinger or Nixon had treated India during the 1971 war. But for Americans, it was a game changer tenure because he had decoupled the dollar with that of the gold standard. And Kissinger was very much responsible for bringing in relating making the dollar uh as a currency through which petrol can be I mean crude oil can be marketed around the world. But now when Trump took power that a meltdown had started the West Asian powers or West Asian countries the
oil producing economies they started to deviate from their normal trend of using dollar as a currency. So they started to deal with their own form of trading between the uh major oil consuming economies. Major oil consuming economies per se is it is nothing. It is not some kind of a what to say uh you need not
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