FROM OPENING INNINGS TO END VICTORY,* *GOOD GOD ,WHAT A SPECTACULAR INNINGS, HEART THROB MOMENTS WERE THERE,* *WHEN CAPTAIN SURYA, HARD HITTING HARDIK FAILED, HERE WAS A SENIOR,OLD TIMER, MODEST, CHAMPION IN EVERY SENSE, PICTURE OF MODESTY, WHAT MORE* *CRICKET TEACHES ONE ALL ESSPIRIT DE CORPS*, *SPORTSMANSHIP SPIRIT* *CRICKET IS A GAME OF GLORIOUS UNCERTAINTIES.* *SO MANY VETERAN COMMENTATORS OF YESTER YEARS COME TO MY MIND.* *MYSELF BROTHER RVRAMESH,ALSO LIC, PLAYED FOR VENKAT CRCKET CLUB LATER PROMOTED TO NEWTON CRICKET CLUB* *LIKE A PANAROMA, VISTAS OF YESTERDAY* *FLOAT BEFORE US, A LIFE, ALLROUND LIF,E WELL LIVED* *TICKTOCK, HEART BEAT MOMENTS ,YET INDOMITABLE SPIRIT PERVADED PERMEATED* *LUCK AND PLUCK COMBINED PLAYED THEIR PART, INDIA WON* I
*NDIA IS ELIGIBLE FOR SEMI FINALS INDIA VS ENGLAND THREE CHEERS TO ALL, EVERY CRICKETER, EVERY SPORTSMAN*
*RBKISHORE*
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(Contd) Hyman M.D., Mark (2023-02-15) Young Forever: THE SUNDAY TIMES BESTSELLER: Hodder & Stoughton: The Jewish faith has a guiding principle—tikkun olam, or the repair of the world, righting the wrongs, facing and addressing injustice and poverty. The gift of reaching sixty-three chronologically but being biologically decades younger gives me the energy and health to be in service of tikkun olam. I am on this journey as a scientist, doctor, and human who wants to explore the wonders of being alive with energy and vitality and joy. I invite you to join me on this journey, to step into a world of health and well-being beyond your wildest imagination. So let’s begin the journey, first to understand the science (I promise I will keep it simple and understandable) and then to describe the principles and practices and program that will keep you young forever. Here’s what you will learn: In Part I, the what—the science of longevity: • The revolution in longevity science • How our current understanding of aging is based on abnormal aging, which is not inevitable • How your biological age can be reversed even as you grow chronologically older • The ten hallmarks of aging—the fundamental problems in our biology that occur with aging • The root causes of the ten hallmarks from the perspective of functional medicine In Part II, the why behind the Young Forever Program: • How to stop and reverse biological aging: optimizing your seven core biological systems • The science behind how to eat for longevity • The science behind how to exercise for longevity • The science of lifestyle practices for longevity • How adversity and little stresses to your system (hormesis) activate longevity pathways • The emerging advances in longevity treatments In Part III, the how—the Young Forever Program: • How to diagnose and test for the underlying causes of aging • Using food as medicine to activate your longevity pathways • Using nutritional supplements for enhancing health span and life span • How to implement simple lifestyle practices and hormesis for longevity • How to personalize your program to address your unique needs and imbalances • My longevity routine: how I apply the longevity revolution to my own health and quest for a long and healthy life span Let’s get started!
Are disease and death preprogrammed events that leave us powerless victims to their inexorable approach? Or is the secret of vitality and longevity buried in our DNA, our molecules, cells, tissues, and biological networks, the interconnected ecosystem that is our human form? Longevity was common in biblical times.
Nobody wants to suffer. And no one wants to live to be 100 or even older in a state of disease and disability. The good news is that you won’t have to if you start to incorporate the principles in this book now—whether you are ten or 100, they work! It is never too late.
The prevailing view is that if people live longer, they will be a burden on society. The opposite is true if that population is healthy. They have wisdom, knowledge, and skills that can improve the social and economic well-being of society overall. And they won’t cost more; in fact, extending healthy life is projected to save trillions and trillions of dollars in our economy. Dr David Sinclair, a professor of genetics at Harvard and leading aging researcher, published an analysis in Nature Aging entitled “The Economic Value of Targeting Aging.” Through rigorous data analysis he estimated that by improving the health span of the average American (shortening or eliminating years of illness during the last 20 percent of their life) and extending life span by one year, we could save $38 trillion a year. If we extend life span across the population by 10 years, we can save $367 trillion—but only if we improve health span. That is nearly ten times the total annual health care expenditure in America alone. Today 90 percent of the United States’ almost $4.1 trillion in health care expenditures is on lifestyle-preventable chronic disease—heart disease, cancer, diabetes, dementia, kidney disease, hypertension, and so on. What is even more frightening is the juggernaut of disease and the overwhelm of our health care system as our currently very unhealthy population ages. A 2018 study found that 88 percent of Americans are in poor metabolic health—meaning they are on their way to heart disease and diabetes and dementia and cancer. Published in 2022, just four years later, another large study found that fewer than 7 percent of Americans are metabolically healthy, in other words, have normal blood pressure, blood sugar, cholesterol, and weight, and have not had a heart attack or stroke! During the COVID‑19 pandemic, 63 percent of hospitalizations could have been avoided by a healthy diet. Those most affected by COVID are the obese, chronically ill, and elderly (who nearly all have a chronic disease). The moral of the story: Focusing on staying healthy pays big dividends in both the quality and length of our lives as we age, and it is never too late to start. we do that? You don’t have to ditch your phone, your job, or your home, or change your genes. By following the principles and the plan in Young Forever you can look forward to a longer life, a life where your health span equals your life span. Longevity Science: Reimagining Aging Before you dismiss the idea that biological aging is an inevitable part of life, imagine if we considered aging a disease. Like other diseases it would have a cause, symptoms, and a natural history. If we didn’t address this disease, eventually we’d die, just as we would from other diseases. Imagine if we reframed our approach to aging. To do this, we must challenge a few entrenched beliefs about aging. First: We must imagine that getting older doesn’t inevitably mean getting weaker, slower, sicker, feebler, or more dependent. Almost everyone knows someone in their nineties who still dances, cooks, drives, spends time with loved ones, reads books, does puzzles, and thoroughly enjoys being alive. It shouldn’t be an anomaly but the norm. Hiking, skydiving, living, and loving past 100 years old should be what we expect.
Second: We must disrupt the existing medical paradigm. The practice of medicine today is reductionist and siloed and ignores the current science that has revealed the body to be one whole integrated system or network. If you have psoriasis, arthritis, heart disease, diabetes, irritable bowel, and depression you may be referred to six different specialists, but all these problems are caused by inflammation. You will be given the best drugs to treat the symptoms of each disease based on the latest medical research, but none of the specialists is likely to address the disease’s root cause. For example, food sensitivities as well as imbalances in the gut and microbiome can cause all these conditions and diseases. They are not separate and distinct problems. Treat the cause or causes, and the symptoms and diseases disappear. Your body is not a set of independent organs. It is a weblike ecosystem. The same root cause can result in multiple different symptoms and conditions. Address the causes and provide the conditions for health, and diseases go away as a side effect. Functional Medicine: A New Approach to Health Care In the groundbreaking textbook from Harvard scientists called Network Medicine: Complex Systems in Disease and Therapeutics, the authors present a radically different view of medicine, a model that challenges our current organ-based, single-disease, single-drug model. They explain it this way: “Network medicine embraces the complexity of multifactorial influences on disease. While network medicine offers a fundamentally different approach toward understanding disease etiology (cause), it will eventually lead to key differences in how diseases are treated—with multiple molecular targets that may require manipulation in a coordinated, dynamic fashion.” The authors referred to this radically different approach to health care as “network medicine”; I and many of my colleagues call it “functional medicine.” Functional medicine suggests that all diseases have a root cause (etiology). We must find and address all the factors or causes that contribute to disease. If your roof is leaking, you need to find the hole and patch it. And if you have multiple holes, you must fix them all. The good news is that most of the root causes are treatable through diet and lifestyle interventions—practices available to almost anyone. This approach will change how we treat disease. Rather than suppressing symptoms with medication, we can map out the root causes and address all of them with multiple simultaneous interventions that restore and enhance optimal function. Functional medicine is the science of creating health. When you create health, disease disappears. The body comprises seven dynamically interconnected, networked systems that underlie all disease—155,000 diseases, in fact. What are these systems? 1. Assimilating nutrients, digestion, and the microbiome 2. Defense and repair (immune and inflammatory system) 3. Energy production (mitochondria) 4. Detoxification 5. Transportation (circulation and lymphatic system) 6. Communication (hormones, neurotransmitters, etc.) 7. The body’s structure (from cellular structures to the musculoskeletal system) When these systems are in dynamic balance, health and longevity are the natural consequences. Disrupt any system and disease and aging occur. Functional medicine provides a road map to assess all the environmental, lifestyle, and predisposing factors—genes, stress, toxins, trauma, microbes, diet, allergens, and so on, that cause imbalance in these systems. We identify the what (symptoms) and the why (too much or too little of what is needed for health) so we can determine the how (removing the impediments to health and adding the ingredients for health). This allows us to focus on the personalized strategies for lifestyle interventions and managing our environment to create the best outcomes, prevent chronic disease, and extend healthy life span.
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